BCG vaccine

{
  "id": "MLC-T-ONC-000951",
  "term": "BCG vaccine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A vaccine used to prevent tuberculosis (TB) in people who are at a high risk of TB or where TB is common. It is rarely given in the U.S. It is made from a weakened form of a bacterium called Mycobacterium bovis (bacillus Calmette-Guérin), which is similar to the bacteria that cause TB. The vaccine may help the body’s immune system make antibodies to destroy the TB bacteria. It also may help the immune system kill cancer cells and is being studied in the treatment of melanoma. Also called bacillus Calmette-Guérin vaccine.",
    "A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine likely activates a Th1 cytokine response that includes the induction of interferon. Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium tuberculosis."
  ],
  "synonyms": [
    "bacillus Calmette-Guérin vaccine",
    "bacillus Calmette-Guerin vaccine",
    "Bacille Calmette Guerin",
    "Bacille Calmette-Guerin live",
    "Bacillius Calmette-Guerin vaccine",
    "Bacillus Calmette Guerin vaccine",
    "Bacillus Calmette-Guerin",
    "BCG",
    "BCG (Pasteur)",
    "BCG Tice",
    "Live intravesical BCG",
    "Mycobacterium bovis (strain BCG)"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bcg-vaccine/"
}