autologous tumor cells/bacillus Calmette-Guérin/formalin-based vaccine

{
  "id": "MLC-T-ONC-011787",
  "term": "autologous tumor cells/bacillus Calmette-Guérin/formalin-based vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A therapeutic personalized breast cancer vaccine composed of autologous tumor cells and bacillus Calmette-Guerin (BCG) in a liquid vehicle containing formalin, with potential immunomodulating and antineoplastic activities. Upon vaccination, the autologous tumor cells/BCG/formalin-based vaccine, which contains an individual’s unique set of tumor-associated antigens (TAAs), may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against the breast cancer cells, resulting in decreased tumor growth. The BCG component serves as an adjuvant, a nonspecific stimulator of the immune response.",
  "synonyms": [
    "autologous tumor cells/BCG/formalin-based vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-tumor-cells-bacillus-calmette-guerin-formalin-based-vaccine/"
}