bispecific antibody JNJ-70218902

{
  "id": "MLC-T-ONC-012038",
  "term": "bispecific antibody JNJ-70218902",
  "field": "Oncology and biomedicine",
  "definition": "A T-cell redirecting agent and bispecific antibody targeting an as of yet undisclosed tumor-associated antigen (TAA) expressed on tumor cells and the CD3 receptor complex expressed on T cells, with potential immunomodulating and antineoplastic activities. Upon administration, bispecific antibody JNJ-70218902 binds to both CD3 on T cells and a TAA expressed on tumor cells. The resulting cross-linkage activates and redirects T cells to the TAA-expressing tumor cells. This results in T-cell-mediated lysis of tumor cells.",
  "synonyms": [
    "T-cell-redirecting agent JNJ-70218902"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bispecific-antibody-jnj-70218902/"
}