bispecific T-cell engager

{
  "id": "MLC-T-ONC-001089",
  "term": "bispecific T-cell engager",
  "field": "Oncology and biomedicine",
  "definition": "A substance made in the laboratory that can bind to two target proteins on the surface of different cells. For example, a bispecific T-cell engager may bind to a certain protein on healthy T cells (a type of immune cell) and, at the same time, to a different protein on cancer cells. This brings the T cells and cancer cells close together so the T cells can more effectively kill the cancer cells. Some bispecific T-cell engagers are being used to treat certain types of cancer, including acute lymphoblastic leukemia, multiple myeloma, lymphoma, and small cell lung cancer. They are a type of targeted therapy. Also called BiTE.",
  "synonyms": [
    "BiTE"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/bispecific-t-cell-engager/"
}