Black seed oil extract supplement

{
  "id": "MLC-T-ONC-012055",
  "term": "Black seed oil extract supplement",
  "field": "Oncology and biomedicine",
  "definition": "An oral supplement composed of the oil extracted from the seeds of Nigella sativa, also known as black seed or black cumin, with potential anti-oxidant, anti-inflammatory, hepatoprotective and immunomodulatory activities. Upon administration of black seed oil extract supplement, the main constituent thymoquinone may stimulate various cytoprotective antioxidant enzymes. Thymoquinone may also exert anti-inflammatory activity by decreasing the production of inflammation mediators, such as tumor necrosis factor (TNF)-alpha, interleukin (IL) 1-beta and IL-6, and inhibiting pro-inflammatory enzymes, including cyclooxygenase (COX). In addition, thymoquinone may modulate the activity of various immune cells such as T cells, B cells, macrophages, neutrophils, natural killer (NK) cells, and dendritic cells (DCs) in the tumor microenvironment (TME) and may enhance anticancer immune responses.",
  "synonyms": [
    "black seed oil extract-based supplement",
    "thymoquinone formula",
    "TQ formula",
    "black seed oil capsule"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/black-seed-oil-extract-supplement/"
}