bone metastasis targeting peptide-11

{
  "id": "MLC-T-ONC-012067",
  "term": "bone metastasis targeting peptide-11",
  "field": "Oncology and biomedicine",
  "definition": "A peptide that mimics naturally occurring interleukin-11 (IL-11) with interleukin receptor binding activity. Upon administration, bone metastasis targeting peptide-11 (BMTP-11) binds to interleukin-11 receptor alpha (IL-11Ra) BMTP-11. This agent might be used to deliver therapeutic agents specifically to IL-11Ra-expressing tumor cells while sparing normal cells. IL-11Ra is a cell surface receptor that may be overexpressed by osteosarcoma cells and by prostate cancer cells in prostate cancer bone metastases.",
  "abbreviation": "BMTP-11",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bone-metastasis-targeting-peptide-11/"
}