anti-IL-11 monoclonal antibody 9MW3811

{
  "id": "MLC-T-ONC-010810",
  "term": "anti-IL-11 monoclonal antibody 9MW3811",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody directed against interleukin-11 (IL-11), with potential anti-fibrotic and antineoplastic activities. Upon administration, anti-IL-11 monoclonal antibody 9MW3811 targets and binds to IL-11. This prevents the binding of IL-11 to interleukin-11 receptor subunit alpha (IL-11RA), and inhibits IL-11-mediated signaling via the gp130/IL-11RA receptor complex. This may decrease fibrosis and inhibit tumor cell proliferation. IL-11, a member of the IL-6 family of cytokines, is upregulated in some fibro-inflammatory diseases and cancers.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-il-11-monoclonal-antibody-9mw3811/"
}