MLchartDataset catalogue

Bruceantin

Term · Oncology and biomedicine · MLC-T-ONC-012134

A triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity.

Table 1. Record
IdentifierMLC-T-ONC-012134
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-012134",
  "term": "Bruceantin",
  "field": "Oncology and biomedicine",
  "definition": "A triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/bruceantin/"
}

Record 3,901 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.