broxuridine

{
  "id": "MLC-T-ONC-001276",
  "term": "broxuridine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug that makes cancer cells more sensitive to radiation and is also used as a diagnostic agent to determine how fast cancer cells grow.",
    "A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks."
  ],
  "abbreviation": "5-BrdU",
  "synonyms": [
    "5-bromodeoxyuridine",
    "bromodeoxyuridine",
    "bromo deoxyuridine",
    "bromouracil deoxyriboside",
    "bromouridine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/broxuridine/"
}