Clonidine-containing mucoadhesive buccal tablet

{
  "id": "MLC-T-ONC-012649",
  "term": "Clonidine-containing mucoadhesive buccal tablet",
  "field": "Oncology and biomedicine",
  "definition": "An extended release, proprietary mucoadhesive buccal tablet formulation containing the hydrochloride salt form of clonidine, the imidazoline derivative and adrenergic alpha 2 receptor agonist, with anti-inflammatory activity. Upon contact of the tablet with the buccal mucosa, clonidine binds to the adrenergic receptors on macrophages and lymphocytes and may reduce the release of pro-inflammatory mediators such as tumor necrosis factor alpha (TNFalpha). As a result, this agent may prevent chemoradiation therapy-induced mucositis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/clonidine-containing-mucoadhesive-buccal-tablet/"
}