collagenase clostridium histolyticum EN3835

{
  "id": "MLC-T-ONC-012704",
  "term": "collagenase clostridium histolyticum EN3835",
  "field": "Oncology and biomedicine",
  "definition": "An injectable formulation composed of the enzyme collagenase produced by the bacterium Clostridium histolyticum and containing a fixed ratio of purified class I (AUX-I) and class II (AUX-II) collagenases, with enzymatic debriding activity. Upon injection of collagenase clostridium histolyticum (CCH) EN3835 to the affected area(s), the collagenase hydrolyzes collagen in the collagen triple helix structure resulting in lysis and solubilization of collagen deposits and plaques. This may promote healing and reduce symptoms caused by excessive collagen deposits and accumulation, such as stiffness of the tissue and pain.",
  "synonyms": [
    "C. clostridium histolyticum EN3835",
    "CCH EN3835"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/collagenase-clostridium-histolyticum-en3835/"
}