MLchartDataset catalogue

Curcumin/polyphenols-containing botanical agent APG-157

Term · Oncology and biomedicine · MLC-T-ONC-012836

An orally bioavailable botanically-based formulation containing multiple polyphenols, including curcumin, the polyphenol derived from the plant Curcuma longa that is also known as turmeric, with potential anti-inflammatory, immunomodulatory and antineoplastic activities. Upon oral administration of curcumin/polyphenols-containing botanical agent APG-157, the curcumin and polyphenols in APG-157 may exert anti-inflammatory activity by decreasing the production of inflammation mediators, such as interleukin (IL) 1-beta, IL-6 and IL-8. The curcumin and polyphenols may also promote T-cell recruitment to the tumor microenvironment (TME) and cytotoxic effects against cancer cells.

Table 1. Record
IdentifierMLC-T-ONC-012836
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-012836",
  "term": "Curcumin/polyphenols-containing botanical agent APG-157",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable botanically-based formulation containing multiple polyphenols, including curcumin, the polyphenol derived from the plant Curcuma longa that is also known as turmeric, with potential anti-inflammatory, immunomodulatory and antineoplastic activities. Upon oral administration of curcumin/polyphenols-containing botanical agent APG-157, the curcumin and polyphenols in APG-157 may exert anti-inflammatory activity by decreasing the production of inflammation mediators, such as interleukin (IL) 1-beta, IL-6 and IL-8. The curcumin and polyphenols may also promote T-cell recruitment to the tumor microenvironment (TME) and cytotoxic effects against cancer cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/curcumin-polyphenols-containing-botanical-agent-apg-157/"
}

Record 5,515 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.