CYP11A1 inhibitor INV-9956

{
  "id": "MLC-T-ONC-012869",
  "term": "CYP11A1 inhibitor INV-9956",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable inhibitor of the enzyme cytochrome 450 side-chain cleavage (scc) (CYP11A1; P450 11A1), with potential antineoplastic activity. Upon oral administration, CYP11A1 inhibitor INV-9956 selectively targets, binds to and inhibits the activity of CYP11A1. This prevents the synthesis of all steroid hormones and their precursors. This may inhibit the proliferation of hormone-positive tumor cells. CYP11A1, a mitochondrial enzyme, catalyzes the conversion of cholesterol to pregnenolone, which is the first rate-limiting step in steroid hormone biosynthesis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cyp11a1-inhibitor-inv-9956/"
}