MLchartDataset catalogue

donor derived HIV-Specific T cells with non-escaped epitope targets

Term · Oncology and biomedicine · MLC-T-ONC-013139

A preparation of ex vivo expanded donor-derived (DD) human immunodeficiency virus (HIV)-specific T cells (HSTs) with non-escaped epitope targets (NEETs), that can potentially be used to eliminate HIV-infected cells and eradicate HIV. Upon administration, DD HST-NEETs target and kill HIV-infected cells, thereby eradicating HIV. HST-NEETs recognize multiple conserved, non-escaped HIV epitopes and their common variants, which is important in killing latently infected cells and could reduce viral escape.

Table 1. Record
IdentifierMLC-T-ONC-013139
FieldOncology and biomedicine
SynonymsDD HST-NEETs; DD-HST-NEETs
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013139",
  "term": "donor derived HIV-Specific T cells with non-escaped epitope targets",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of ex vivo expanded donor-derived (DD) human immunodeficiency virus (HIV)-specific T cells (HSTs) with non-escaped epitope targets (NEETs), that can potentially be used to eliminate HIV-infected cells and eradicate HIV. Upon administration, DD HST-NEETs target and kill HIV-infected cells, thereby eradicating HIV. HST-NEETs recognize multiple conserved, non-escaped HIV epitopes and their common variants, which is important in killing latently infected cells and could reduce viral escape.",
  "synonyms": [
    "DD HST-NEETs",
    "DD-HST-NEETs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/donor-derived-hiv-specific-t-cells-with-non-escaped-epitope-targets/"
}

Record 6,173 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.