donor derived HIV-Specific T cells with non-escaped epitope targets
Term · Oncology and biomedicine · MLC-T-ONC-013139
A preparation of ex vivo expanded donor-derived (DD) human immunodeficiency virus (HIV)-specific T cells (HSTs) with non-escaped epitope targets (NEETs), that can potentially be used to eliminate HIV-infected cells and eradicate HIV. Upon administration, DD HST-NEETs target and kill HIV-infected cells, thereby eradicating HIV. HST-NEETs recognize multiple conserved, non-escaped HIV epitopes and their common variants, which is important in killing latently infected cells and could reduce viral escape.
| Identifier | MLC-T-ONC-013139 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | DD HST-NEETs; DD-HST-NEETs |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013139",
"term": "donor derived HIV-Specific T cells with non-escaped epitope targets",
"field": "Oncology and biomedicine",
"definition": "A preparation of ex vivo expanded donor-derived (DD) human immunodeficiency virus (HIV)-specific T cells (HSTs) with non-escaped epitope targets (NEETs), that can potentially be used to eliminate HIV-infected cells and eradicate HIV. Upon administration, DD HST-NEETs target and kill HIV-infected cells, thereby eradicating HIV. HST-NEETs recognize multiple conserved, non-escaped HIV epitopes and their common variants, which is important in killing latently infected cells and could reduce viral escape.",
"synonyms": [
"DD HST-NEETs",
"DD-HST-NEETs"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/donor-derived-hiv-specific-t-cells-with-non-escaped-epitope-targets/"
}
Record 6,173 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.