Eflornithine hydrochloride ointment
Term · Oncology and biomedicine · MLC-T-ONC-013226
An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered topically, eflornithine irreversibly inhibits skin ODC activity, thereby inhibiting the synthesis of polyamines; inhibition of polyamine synthesis may result in diminished hair growth and epidermal cell turnover.
| Identifier | MLC-T-ONC-013226 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | DL-alpha-difluoromethylornitine hydrochloride ointment |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013226",
"term": "Eflornithine hydrochloride ointment",
"field": "Oncology and biomedicine",
"definition": "An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered topically, eflornithine irreversibly inhibits skin ODC activity, thereby inhibiting the synthesis of polyamines; inhibition of polyamine synthesis may result in diminished hair growth and epidermal cell turnover.",
"synonyms": [
"DL-alpha-difluoromethylornitine hydrochloride ointment"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/eflornithine-hydrochloride-ointment/"
}
Record 6,407 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.