MLchartDataset catalogue

Eflornithine hydrochloride ointment

Term · Oncology and biomedicine · MLC-T-ONC-013226

An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered topically, eflornithine irreversibly inhibits skin ODC activity, thereby inhibiting the synthesis of polyamines; inhibition of polyamine synthesis may result in diminished hair growth and epidermal cell turnover.

Table 1. Record
IdentifierMLC-T-ONC-013226
FieldOncology and biomedicine
SynonymsDL-alpha-difluoromethylornitine hydrochloride ointment
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013226",
  "term": "Eflornithine hydrochloride ointment",
  "field": "Oncology and biomedicine",
  "definition": "An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered topically, eflornithine irreversibly inhibits skin ODC activity, thereby inhibiting the synthesis of polyamines; inhibition of polyamine synthesis may result in diminished hair growth and epidermal cell turnover.",
  "synonyms": [
    "DL-alpha-difluoromethylornitine hydrochloride ointment"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/eflornithine-hydrochloride-ointment/"
}

Record 6,407 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.