eicosapentaenoic acid

{
  "id": "MLC-T-ONC-013288",
  "term": "eicosapentaenoic acid",
  "field": "Oncology and biomedicine",
  "definition": "An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes.",
  "abbreviation": "EPA",
  "synonyms": [
    "icosapentaenoic acid",
    "timnodonic acid",
    "all cis-5,8,11,14,17-eicosapentaenoic acid"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/eicosapentaenoic-acid/"
}