emepepimut-S
Term · Oncology and biomedicine · MLC-T-ONC-013321
A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination, emepepimut-S may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that is overexpressed on the cell surfaces of many epithelial tumor cells as well as on the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells.
| Identifier | MLC-T-ONC-013321 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | BP1-7-KLH |
| Synonyms | tecemotide; liposomal BLP25 vaccine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013321",
"term": "emepepimut-S",
"field": "Oncology and biomedicine",
"definition": "A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination, emepepimut-S may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that is overexpressed on the cell surfaces of many epithelial tumor cells as well as on the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells.",
"abbreviation": "BP1-7-KLH",
"synonyms": [
"tecemotide",
"liposomal BLP25 vaccine"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/emepepimut-s/"
}
Record 6,585 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.