eniluracil

{
  "id": "MLC-T-ONC-002849",
  "term": "eniluracil",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An anticancer drug that increases the effectiveness of fluorouracil. Also called ethynyluracil.",
    "An orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU."
  ],
  "synonyms": [
    "ethynyluracil",
    "5-ethynyluracil"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/eniluracil/"
}