eniluracil/5-FU combination tablet

{
  "id": "MLC-T-ONC-013354",
  "term": "eniluracil/5-FU combination tablet",
  "field": "Oncology and biomedicine",
  "definition": "A combination tablet of ethynyluracil and fluorouracil. Fluorouracil is an antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Ethynyluracil is an orally-active fluoropyrimidine analog that inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil in the liver. This may lead to an increase in the bioavailability and, effectiveness of fluorouracil.",
  "synonyms": [
    "776C85/5-FU",
    "ethynyluracil/fluorouracil",
    "GW776/5-fluorouracil",
    "GW776/5-FU"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/eniluracil-5-fu-combination-tablet/"
}