Epothilone D

{
  "id": "MLC-T-ONC-002928",
  "term": "Epothilone D",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance being studied in the treatment of cancer. It is a type of mitotic inhibitor and epothilone. Also called KOS-862.",
    "A natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Also known as desoxyepothilone B, epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility."
  ],
  "synonyms": [
    "KOS-862",
    "desoxyepothilone B",
    "12,13-Deoxyepothilone B"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/epothilone-d/"
}