esketamine

{
  "id": "MLC-T-ONC-013430",
  "term": "esketamine",
  "field": "Oncology and biomedicine",
  "definition": "A cyclohexanone derivative and S-enantiomer of racemic ketamine, with analgesic, anesthetic and antidepressant activities. Although the mechanism of action is not fully understood, upon administration, esketamine targets, non-competitively binds to, and blocks N-methyl D-aspartate (NMDA) receptors. This reduces pain perception, induces sedation, and produce dissociative anesthesia.",
  "synonyms": [
    "L-ketamine",
    "ketamine, S-"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/esketamine/"
}