intranasal ketamine

{
  "id": "MLC-T-ONC-014486",
  "term": "intranasal ketamine",
  "field": "Oncology and biomedicine",
  "definition": "An intranasal formualtion of the synthetic cyclohexanone ketamine with analgesic and anesthetic activities. Although its mechanism of action is not well understood, ketamine appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and agonistically bind to and activate opiod mu and sigma receptors, thereby reducing pain perception, inducing sedation, and producing dissociative anesthesia.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/intranasal-ketamine/"
}