MLchartDataset catalogue

etanidazole

Term · Oncology and biomedicine · MLC-T-ONC-013446

A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases.

Table 1. Record
IdentifierMLC-T-ONC-013446
FieldOncology and biomedicine
Synonyms2-nitro-imidazole derivative
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013446",
  "term": "etanidazole",
  "field": "Oncology and biomedicine",
  "definition": "A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases.",
  "synonyms": [
    "2-nitro-imidazole derivative"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/etanidazole/"
}

Record 6,946 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.