N-methylformamide

{
  "id": "MLC-T-ONC-015530",
  "term": "N-methylformamide",
  "field": "Oncology and biomedicine",
  "definition": "A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells.",
  "abbreviation": "NMF",
  "synonyms": [
    "formylmethylamine",
    "monomethylformamide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/n-methylformamide/"
}