tempol-containing MBM-02

{
  "id": "MLC-T-ONC-017060",
  "term": "tempol-containing MBM-02",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable gelatin capsule-based formulation containing tempol, a hydrophilic piperidine nitroxide, with potential chemo/radioprotective and antioxidant activities. Upon oral administration of MBM-02, tempol, being a free radical compound, may be able to protect cells against the damaging effects of reactive oxygen species (ROS), upon exposure to ionizing radiation and oxidative stress. MBM-02 may selectively protect normal tissue from chemotherapy- and radiation-induced toxicities. Tempol is in its protective form in oxygenated cells and is in its unprotective form in the hypoxic tumor microenvironment (TME).",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tempol-containing-mbm-02/"
}