MLchartDataset catalogue

Ethosuximide

Term · Oncology and biomedicine · MLC-T-ONC-013456

A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.

Table 1. Record
IdentifierMLC-T-ONC-013456
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013456",
  "term": "Ethosuximide",
  "field": "Oncology and biomedicine",
  "definition": "A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ethosuximide/"
}

Record 6,965 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.