ex vivo-activated autologous lymph node lymphocytes

{
  "id": "MLC-T-ONC-013479",
  "term": "ex vivo-activated autologous lymph node lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "Autologous human lymph node T-lymphocytes, with potential immunostimulatory and antineoplastic activity. Upon collection of immune cells from the tumor-draining lymph node, the human lymph node lymphocytes are activated with anti-CD3/anti-CD28 microbeads, cultured with recombinant, human interleukin-2 (IL-2), expanded and isolated ex vivo. Upon reintroduction into the patient, the ex vivo-activated autologous lymph node lymphocytes recognize and lyse the tumor cells.",
  "synonyms": [
    "X-ACT autologous lymph node lymphocytes",
    "X-ACT"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ex-vivo-activated-autologous-lymph-node-lymphocytes/"
}