ferumoxtran-10

{
  "id": "MLC-T-ONC-003174",
  "term": "ferumoxtran-10",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance being studied as a way of improving magnetic resonance imaging (MRI) in diagnosing cancer and finding lymph nodes to which cancer has spread. Ferumoxtran-10 is made of nanoparticles (ultrasmall pieces) of iron oxide coated with dextran (a type of sugar). It is injected into the blood of the patient and the particles collect in lymph nodes, liver, spleen, or brain tissue where they can be seen using MRI. Ferumoxtran-10 later breaks down and passes from the body in urine.",
    "A synthetic ultrasmall superparamagnetic iron oxide composed of dextran-coated iron oxide nanoparticles (also known as 'ultrasmall particulate iron oxides' or USPIO). Ferumoxtran-10, which accumulates in non-cancerous lymphatic tissue, is used as a molecular resonance imaging (MRI) contrast agent."
  ],
  "abbreviation": "USPIO",
  "synonyms": [
    "Ultrasmall Particulate Iron Oxide"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ferumoxtran-10/"
}