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ferumoxytol non-stoichiometric magnetite

Term · Oncology and biomedicine · MLC-T-ONC-013571

A superparamagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic carbohydrate, polyglucose sorbitol carboxymethyl ether, with potential anti-anemic and imaging properties. After intravenous administration, ferumoxytol replaces iron stores with fewer side effects compared to the use of oral iron. In addition, this agent generates T1 relaxation, producing a magnetic field and enhancing T2 relaxation, thereby darkening contrast media-containing structures in magnetic resonance imaging (MRI). Due to small particle size, ferumoxytol remains in the intravasculature for a prolonged period and so may be used as a blood pool agent.

Table 1. Record
IdentifierMLC-T-ONC-013571
FieldOncology and biomedicine
AbbreviationFe3O4
Synonymsblack iron oxide; ferrosoferric oxide; iron black; magnetic black; magnetite; Sienna+
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013571",
  "term": "ferumoxytol non-stoichiometric magnetite",
  "field": "Oncology and biomedicine",
  "definition": "A superparamagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic carbohydrate, polyglucose sorbitol carboxymethyl ether, with potential anti-anemic and imaging properties. After intravenous administration, ferumoxytol replaces iron stores with fewer side effects compared to the use of oral iron. In addition, this agent generates T1 relaxation, producing a magnetic field and enhancing T2 relaxation, thereby darkening contrast media-containing structures in magnetic resonance imaging (MRI). Due to small particle size, ferumoxytol remains in the intravasculature for a prolonged period and so may be used as a blood pool agent.",
  "abbreviation": "Fe3O4",
  "synonyms": [
    "black iron oxide",
    "ferrosoferric oxide",
    "iron black",
    "magnetic black",
    "magnetite",
    "Sienna+"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ferumoxytol-non-stoichiometric-magnetite/"
}

Record 7,237 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.