ferumoxytol non-stoichiometric magnetite
Term · Oncology and biomedicine · MLC-T-ONC-013571
A superparamagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic carbohydrate, polyglucose sorbitol carboxymethyl ether, with potential anti-anemic and imaging properties. After intravenous administration, ferumoxytol replaces iron stores with fewer side effects compared to the use of oral iron. In addition, this agent generates T1 relaxation, producing a magnetic field and enhancing T2 relaxation, thereby darkening contrast media-containing structures in magnetic resonance imaging (MRI). Due to small particle size, ferumoxytol remains in the intravasculature for a prolonged period and so may be used as a blood pool agent.
| Identifier | MLC-T-ONC-013571 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | Fe3O4 |
| Synonyms | black iron oxide; ferrosoferric oxide; iron black; magnetic black; magnetite; Sienna+ |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013571",
"term": "ferumoxytol non-stoichiometric magnetite",
"field": "Oncology and biomedicine",
"definition": "A superparamagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic carbohydrate, polyglucose sorbitol carboxymethyl ether, with potential anti-anemic and imaging properties. After intravenous administration, ferumoxytol replaces iron stores with fewer side effects compared to the use of oral iron. In addition, this agent generates T1 relaxation, producing a magnetic field and enhancing T2 relaxation, thereby darkening contrast media-containing structures in magnetic resonance imaging (MRI). Due to small particle size, ferumoxytol remains in the intravasculature for a prolonged period and so may be used as a blood pool agent.",
"abbreviation": "Fe3O4",
"synonyms": [
"black iron oxide",
"ferrosoferric oxide",
"iron black",
"magnetic black",
"magnetite",
"Sienna+"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/ferumoxytol-non-stoichiometric-magnetite/"
}
Record 7,237 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.