Fibrin sealant

{
  "id": "MLC-T-ONC-003187",
  "term": "Fibrin sealant",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance used during surgery to help heal wounds. It contains proteins found in human blood that cause blood to clot. When fibrin sealant is placed on a wound, a clot forms. Fibrin sealant is being studied as a way to improve healing after lymph node removal in patients with cancer. It is a type of surgical glue.",
    "A plasma-derived fibrin biomatrix preparation consisting of two separate solutions that are combined on application. The sealer protein solution contains clottable human fibrinogen and bovine aprotinin, a fibrinolysis inhibitor; the thrombin solution contains human thrombin and calcium chloride. When the solutions are combined, a clot is formed, reproducing the final stages of the coagulation cascade."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fibrin-sealant/"
}