NHS-POx-based hemostatic sealant patch

{
  "id": "MLC-T-ONC-015501",
  "term": "NHS-POx-based hemostatic sealant patch",
  "field": "Oncology and biomedicine",
  "definition": "A sterile resorbable hemostatic sealing patch composed of porcine gelatin fiber-based carrier loaded with N-hydroxy-succinimide polyoxazoline (NHS-POx) polymer and nucleophilically activated polyoxazoline (NU-POx) granulate, with potential hemostatic activity. Upon application on the wound tissue, the coagulation cascade is started. A matrix of platelet aggregation is formed, and a fibrin clot is formed in the gelatin fibers. This combines with NHS-POx and NU-POx to form POx-hydrogel, which promotes hemostasis.",
  "synonyms": [
    "GATT-Patch"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/nhs-pox-based-hemostatic-sealant-patch/"
}