FLT3/KIT kinase inhibitor AKN-028

{
  "id": "MLC-T-ONC-013635",
  "term": "FLT3/KIT kinase inhibitor AKN-028",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3; STK1) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity. FLT3/KIT kinase inhibitor AKN-028 binds to and inhibits both the wild-type and mutated forms of FLT3 and SCFR. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these receptor tyrosine kinases.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/flt3-kit-kinase-inhibitor-akn-028/"
}