Fosaprepitant dimeglumine

{
  "id": "MLC-T-ONC-013755",
  "term": "Fosaprepitant dimeglumine",
  "field": "Oncology and biomedicine",
  "definition": "The dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fosaprepitant-dimeglumine/"
}