ibandronate sodium

{
  "id": "MLC-T-ONC-014291",
  "term": "ibandronate sodium",
  "field": "Oncology and biomedicine",
  "definition": "The sodium salt of ibadronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain.",
  "synonyms": [
    "ibandronate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ibandronate-sodium/"
}