IgM-enriched immunoglobulins

{
  "id": "MLC-T-ONC-014338",
  "term": "IgM-enriched immunoglobulins",
  "field": "Oncology and biomedicine",
  "definition": "An immunoglobulin preparation consisting of immunoglobulin G (IgG) and immunoglobulin A (IgA), supplemented with immunoglobulin M (IgM), with potential antibacterial and immunomodulatory properties. Upon intravenous administration, IgM-enriched immunoglobulins may increase the elimination of infectious pathogens in comparison to immunoglobulin regimens lacking IgM. IgM is the major immunoglobulin secreted during the primary immune response and plays a significant role in compliment activation and in the neutralization of bacterial endo- and exotoxins.",
  "synonyms": [
    "pentaglobin",
    "ivIgGMA",
    "immunoglobulin M-enriched immunoglobulins",
    "IgM-enriched immunoglobulin",
    "immunoglobulin GMA"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/igm-enriched-immunoglobulins/"
}