Imsidolimab

{
  "id": "MLC-T-ONC-014397",
  "term": "Imsidolimab",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody directed against the interleukin-36 receptor (IL-36R), with potential anti-inflammatory and immunomodulatory activities. Upon administration, imsidolimab targets, binds to and prevents the activity of IL-36R by the pro-inflammatory cytokine IL-36. This prevents IL-36/IL-36R-mediated signaling pathways. This may inhibit skin inflammation in which the IL-36/IL-36R plays a key role. IL-36 is highly upregulated in certain skin inflammatory conditions.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/imsidolimab/"
}