inherited cancer syndrome

{
  "id": "MLC-T-ONC-004327",
  "term": "inherited cancer syndrome",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A type of inherited disorder in which there is a higher-than-normal risk of certain types of cancer. Inherited cancer syndromes are caused by mutations (changes) in certain genes passed from parents to children. In an inherited cancer syndrome, certain patterns of cancer may be seen within families. These patterns include having several close family members (such as a mother, daughter, and sister) with the same type of cancer, developing cancer at an early age, or having two or more types of cancer develop in the same person. Examples of inherited cancer syndromes are hereditary breast and ovarian cancer syndrome, Li-Fraumeni syndrome, Cowden syndrome, and Lynch syndrome. Also called family cancer syndrome and hereditary cancer syndrome.",
    "A type of inherited disorder in which there is a higher-than-normal risk of certain types of cancer. Inherited cancer syndromes are caused by inherited genetic variants and may be associated with several clinical manifestations. Examples of inherited cancer syndromes include Lynch syndrome and hereditary breast and ovarian cancer syndrome. Also called family cancer syndrome and hereditary cancer syndrome."
  ],
  "synonyms": [
    "family cancer syndrome",
    "hereditary cancer syndrome"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/inherited-cancer-syndrome/"
}