JAK inhibitor

{
  "id": "MLC-T-ONC-004568",
  "term": "JAK inhibitor",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance that blocks the action of enzymes called Janus-associated kinases (JAK1, JAK2, JAK3, and TYK2), which help control cell signaling and growth, the number of blood cells and platelets that are made in the bone marrow, inflammation, and immune cell activity. Blocking these enzymes may help keep abnormal blood cells or cancer cells from growing. It may also reduce inflammation. Some JAK inhibitors are used to treat cancer. They are a type of targeted therapy. Also called Janus kinase inhibitor.",
    "Any agent that targets, binds to and inhibits the activity of one or more of the Janus kinase family of enzymes."
  ],
  "synonyms": [
    "Janus kinase inhibitor"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/jak-inhibitor/"
}