Janus kinase inhibitor

{
  "id": "MLC-T-ONC-004572",
  "term": "Janus kinase inhibitor",
  "field": "Oncology and biomedicine",
  "definition": "A substance that blocks the action of enzymes called Janus-associated kinases (JAK1, JAK2, JAK3, and TYK2), which help control cell signaling and growth, the number of blood cells and platelets that are made in the bone marrow, inflammation, and immune cell activity. Blocking these enzymes may help keep abnormal blood cells or cancer cells from growing. It may also reduce inflammation. Some Janus kinase inhibitors are used to treat cancer. They are a type of targeted therapy. Also called JAK inhibitor.",
  "synonyms": [
    "JAK inhibitor"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/janus-kinase-inhibitor/"
}