Kallikrein inhibitor MDPK67b

{
  "id": "MLC-T-ONC-014628",
  "term": "Kallikrein inhibitor MDPK67b",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant protein-based inhibitor of numerous types of kallikrein-related peptidases (KLKs), with potential antineoplastic activity. Upon administration, KLK inhibitor MDPK67b targets and inhibits various KLKs, including KLK2, KLK4, KLK5 and KLK14. This inhibits KLK-mediated signaling and inhibits the proliferation of tumor cells in which these KLKs are overexpressed. Deregulation of KLKs is associated with some types of cancers.",
  "synonyms": [
    "KLK inhibitor MDPK67b"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/kallikrein-inhibitor-mdpk67b/"
}