anti-KLK2 CAR T cells JNJ-75229414

{
  "id": "MLC-T-ONC-010838",
  "term": "anti-KLK2 CAR T cells JNJ-75229414",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting human kallikrein-2 (hK2; KLK2) expressed on tumor cells, with potential immunostimulating and antineoplastic activities. Upon administration, anti-KLK2 CAR T cells JNJ-75229414 target and bind to KLK2-expressing tumor cells, thereby inducing selective toxicity in KLK2-expressing tumor cells. KLK2 is overexpressed in certain tumors, including prostate adenocarcinoma.",
  "synonyms": [
    "anti-kallikrein-2 CAR T cells JNJ-75229414",
    "KLK2 CAR-T cells JNJ-75229414"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-klk2-car-t-cells-jnj-75229414/"
}