Monoclonal antibody AK002

{
  "id": "MLC-T-ONC-015252",
  "term": "Monoclonal antibody AK002",
  "field": "Oncology and biomedicine",
  "definition": "A therapeutic monoclonal antibody against an as-of-yet unidentified target expressed on mast cells and eosinophils. Upon administration, AK002 targets and binds to a receptor expressed on the surface of mast cells and eosinophils. This may induce antibody-dependent cell-mediated cytotoxicity (ADCC) against cells overexpressing the undisclosed receptor. This may reduce abnormal proliferation of mast cells and eosinophils, which play a key role in allergic and inflammatory responses.",
  "synonyms": [
    "monoclonal antibody AK 002"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/monoclonal-antibody-ak002/"
}