MLchartDataset catalogue

Natural killer cells ZRx101

Term · Oncology and biomedicine · MLC-T-ONC-015445

A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma.

Table 1. Record
IdentifierMLC-T-ONC-015445
FieldOncology and biomedicine
SynonymsNK cells ZRx101
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015445",
  "term": "Natural killer cells ZRx101",
  "field": "Oncology and biomedicine",
  "definition": "A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma.",
  "synonyms": [
    "NK cells ZRx101"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/natural-killer-cells-zrx101/"
}

Record 11,622 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.