R-1,3-butanediol-based supplement

{
  "id": "MLC-T-ONC-016333",
  "term": "R-1,3-butanediol-based supplement",
  "field": "Oncology and biomedicine",
  "definition": "A supplement composed of R-1,3-butanediol that may be used to increase the level of the ketone body beta-hydroxybutyrate (BHB), with potential protective and antineoplastic activities. Upon administration of R-1,3-butanediol-based supplement, R-1,3-butanediol is converted to BHB. BHB may activate the surface receptor hydroxycarboxylic acid receptor 2 (HCAR2) and induce the transcriptional regulator homeodomain-only protein (HOPX), thereby inhibiting cell proliferation in intestinal epithelial cells that express HCAR2 and HOPX.",
  "synonyms": [
    "beta-hydroxybutyrate supplement",
    "R-1,3-butanediol supplement"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/r-13-butanediol-based-supplement/"
}