recombinant human papillomavirus quadrivalent vaccine

{
  "id": "MLC-T-ONC-007258",
  "term": "recombinant human papillomavirus quadrivalent vaccine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A vaccine that is no longer available in the United States but is still used in other countries to protect against infection with four types of human papillomavirus (HPV). Recombinant human papillomavirus quadrivalent vaccine is used in females and males aged 9 to 26 years to protect against low-risk HPV types 6 and 11, which cause most genital warts, and against high-risk HPV types 16 and 18, which cause most precancerous lesions and cancers of the cervix, vagina, vulva, and anus. Recombinant human papillomavirus quadrivalent vaccine may also prevent HPV-related cancers of the penis and oropharynx. Also called Gardasil.",
    "A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity. The immunoprohylactic efficacy of L1 VLP vaccines, such as recombinant human papillomavirus quadrivalent vaccine, appear to be mediated by the development of humoral immune responses. HPV Types 16 and 18 account for approximately 70% of cervical cancers and HPV Types 6 and 11 account for approximately 90% of genital warts."
  ],
  "synonyms": [
    "Gardasil",
    "quadrivalent HPV (type 6, 11, 16 and 18) L1 virus-like particle vaccine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-human-papillomavirus-quadrivalent-vaccine/"
}