recombinant vaccinia-CEA(6D)-TRICOM vaccine

{
  "id": "MLC-T-ONC-016468",
  "term": "recombinant vaccinia-CEA(6D)-TRICOM vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A vaccine consisting of recombinant vaccinia virus encoding the tumor-associated antigen carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-CEA(6D)-TRICOM vaccine stimulates the host immune system to mount a T-cell response against tumor cells expressing the CEA antigen. The use of TRICOM in the vaccine may elicit a greater antitumor cytotoxic T lymphocyte (CTL) immune response compared to the use of vaccinia-CEA alone.",
  "synonyms": [
    "rV-CEA(6D)-TRICOM"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-vaccinia-cea-6d-tricom-vaccine/"
}