MLchartDataset catalogue

Rhenium Re 188 etidronate

Term · Oncology and biomedicine · MLC-T-ONC-016530

A synthetic compound containing the bisphosphonate etidronate (hydroxyethylidene diphosphonate, HEDP) labeled with rhenium Re188, a beta-emitting radioisotope with potential antineoplastic activity. Upon administration, Re-188 etidronate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. The beta-radiation may provide localized anti-tumor radiotoxicity while sparing extramedullary bone marrow tissues.

Table 1. Record
IdentifierMLC-T-ONC-016530
FieldOncology and biomedicine
Synonymsrhenium Re 188-HEDP; rhenium-188-HEDP; Re 188 hydroxyethylidene diphosphonate; rhenium-188 HEDP; Re-188 HEDP; 188Re-HEDP; Re-188 hydroxyethylidene diphosphonate; Re 188 etidronic acid; rhenium-188 etidronate; Re-188 etidronate; 188Re-etidronate; Re-188etidronate; rhenium Re-188 hydroxyethylidene diphosphonate
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016530",
  "term": "Rhenium Re 188 etidronate",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic compound containing the bisphosphonate etidronate (hydroxyethylidene diphosphonate, HEDP) labeled with rhenium Re188, a beta-emitting radioisotope with potential antineoplastic activity. Upon administration, Re-188 etidronate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. The beta-radiation may provide localized anti-tumor radiotoxicity while sparing extramedullary bone marrow tissues.",
  "synonyms": [
    "rhenium Re 188-HEDP",
    "rhenium-188-HEDP",
    "Re 188 hydroxyethylidene diphosphonate",
    "rhenium-188 HEDP",
    "Re-188 HEDP",
    "188Re-HEDP",
    "Re-188 hydroxyethylidene diphosphonate",
    "Re 188 etidronic acid",
    "rhenium-188 etidronate",
    "Re-188 etidronate",
    "188Re-etidronate",
    "Re-188etidronate",
    "rhenium Re-188 hydroxyethylidene diphosphonate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/rhenium-re-188-etidronate/"
}

Record 14,446 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.