MLchartDataset catalogue

ROS1 inhibitor JYP0322

Term · Oncology and biomedicine · MLC-T-ONC-016585

An orally available selective inhibitor of the receptor tyrosine kinase c-ros oncogene 1 (ROS1), with potential antineoplastic activity. Upon oral administration, ROS1 inhibitor JYP0322 targets, binds to and inhibits ROS1. This inhibits proliferation of ROS1-driven tumor cells. ROS1, overexpressed, rearranged and/or mutated in certain cancer cells, plays a key role in cell growth and survival of various types of cancer cells.

Table 1. Record
IdentifierMLC-T-ONC-016585
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016585",
  "term": "ROS1 inhibitor JYP0322",
  "field": "Oncology and biomedicine",
  "definition": "An orally available selective inhibitor of the receptor tyrosine kinase c-ros oncogene 1 (ROS1), with potential antineoplastic activity. Upon oral administration, ROS1 inhibitor JYP0322 targets, binds to and inhibits ROS1. This inhibits proliferation of ROS1-driven tumor cells. ROS1, overexpressed, rearranged and/or mutated in certain cancer cells, plays a key role in cell growth and survival of various types of cancer cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ros1-inhibitor-jyp0322/"
}

Record 14,568 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.