sovateltide

{
  "id": "MLC-T-ONC-016833",
  "term": "sovateltide",
  "field": "Oncology and biomedicine",
  "definition": "A highly selective peptide agonist of the endothelin-B receptor. Sovateltide binds to endothelin-B receptors on endothelial cells in tumor blood vessels, which, unlike the angioarchitecture of normal blood vessels, are relatively devoid of smooth muscle. This agent may induce a transient, selective increase in blood flow to a tumor, which may result in an increase in the delivery of anticancer agents to the tumor and, so, an increase in anticancer agent efficacy.",
  "synonyms": [
    "endothelin B receptor agonist SPI-1620"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sovateltide/"
}