Tasisulam sodium

{
  "id": "MLC-T-ONC-016992",
  "term": "Tasisulam sodium",
  "field": "Oncology and biomedicine",
  "definition": "The sodium salt form of tasisulam, an acyl-sulfonamide compound with potential antiproliferative activity. Tasisulam activates, through an as of yet not fully elucidated mechanism, the intrinsic mitochondrial-mediated cell death pathway as manifested by decreased adenosine triphosphate (ATP), cytochrome C release, activation of caspases, loss of mitochondrial membrane potential, production of reactive oxygen species (ROS) and eventually apoptosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tasisulam-sodium/"
}